In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway.
نویسندگان
چکیده
Previous studies have shown that fosmidomycin, risedronate, and nerolidol exert antimalarial activity in vitro. We included squalestatin, an inhibitor of the isoprenoid metabolism in Erwinia uredovora, and found that combinations of compounds which act on different targets of the plasmodial isoprenoid pathway possess important supra-additivity effects.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 59 8 شماره
صفحات -
تاریخ انتشار 2015